Brit J Cancer:高强度间歇训练对睾丸癌幸存者疲劳及生活质量的影响!

2018-05-13 xing.T MedSci原创

由此可见,HIIT能显著改善TCS患者的CRF和HRQoL。通过心肺功能的介导和受到临床特征的调节,提示有针对性的运动干预可以优化TCS患者的PROs。

睾丸癌幸存者(TCS)癌症相关的疲劳(CRF)、心理社会功能受损和不良心理健康相关的生活质量(HRQoL)风险有所增加。近日,肿瘤领域权威杂志British Journal of Cancer上发表了一篇研究文章,研究人员分析了高强度间隔训练(HIIT)对TCS患者报告的结局(PROs)的影响。其次,研究人员探讨了心肺适能作为干预效果中介因素的作用,并选择作为干预效果调节因子的基线特征。

研究人员将TCS患者(n=63)随机分为接受12周督导的HIIT或常规护理(UC)。PROs包括基线、干预后和随访3个月的CRF、抑郁、焦虑、应激、自尊、睡眠质量和HRQoL。

TCS患者(诊断后中位数为7年)完成了99%的训练课程,达到了98%的目标训练强度。ANCOVA显示,与UC相比,HIIT可显著改善了干预后CRF(P=0.003)、自尊(P=0.029)和多个HRQoL领域(Ps<0.05)。随访3个月,对CRF(P=0.031)和活力(P=0.015)的影响仍然存在。心肺适应性可由CRF和HRQOL改善的介导而有所改善。对于基线较少运动生活方式、低体适能、高睾酮水平和临床疲劳的TCS患者CRF的效应更大。

由此可见,HIIT能显著改善TCS患者的CRF和HRQoL。通过心肺功能的介导和受到临床特征的调节,提示有针对性的运动干预可以优化TCS患者的PROs。

原始出处:

Scott C Adams, et al. Effects of high-intensity interval training on fatigue and quality of life in testicular cancer survivors. British Journal of Cancer. 2018. https://www.nature.com/articles/s41416-018-0044-7

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    2018-05-15 1209e435m98(暂无昵称)

    学习了.谢谢分享

    0

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    2018-05-15 大爰

    学习了谢谢分享!!

    0

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    2018-05-15 tamgche
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    2018-05-15 zhangph
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    2018-05-15 aids219
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    2018-05-13 1ddf0692m34(暂无匿称)

    学习了.长知识

    0

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    2018-05-13 1e0f8808m18(暂无匿称)

    好文章.学习了.

    0

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岁数越来越大但并不意味着身体会越来越虚弱。一项临床前研究表明,短期高强度间歇性训练可以在高龄时安全地进行,且这种运动具有逆转虚弱的潜力。

JCEM:12周有氧高强度间歇训练后大脑葡萄糖摄取增加!

由此可见,成人进行HIIT训练12周后大脑中减少阿尔茨海默氏病发病的脑区葡萄糖代谢增加。

Diabetes:单次高强度间歇训练可以减少1型糖尿病患者低血糖的发生!

目前的研究结果表明单次HIIT会迅速降低1型糖尿病患者和NAH患者随后低血糖的意识,但不影响IAH患者,减轻低血糖引起的认知功能障碍。运动诱导的乳酸在介导这些效应中的作用,可能是通过作为大脑的替代燃料,应进一步进行探讨。