Stroke:主动脉瘤或夹层修复术后脊髓梗死发生率分析!

2017-06-28 xing.T MedSci原创

由此可见,在主动脉夹层或主动脉瘤破裂患者修补术后脊髓梗死的发生约为每130例患者有1例,而在未破裂的主动脉瘤修复术后约为每600例患者出现1例。

主动脉瘤或主动脉夹层接受手术或腔内修复术后脊髓梗塞的发生率尚不明确。

近日,卒中领域权威杂志Stroke上发表了一篇研究文章,研究人员利用行政索赔数据确定了来自于加利福尼亚的非联邦急性护理医院出院的成年患者和在2005年和2013年期间于佛罗里达州接受手术或腔内修复的主动脉瘤或夹层患者。在主动脉修补前被诊断为脊髓梗塞的患者被排除在外。该研究的主要结局是在主动脉修复住院期间发生的脊髓梗塞。描述性统计被用来估计脊髓梗塞的粗略发生率。根据动脉瘤或夹层是否破裂和修复类型(外科手术和腔内治疗)进行分层分析。

研究人员确定了91212例主动脉瘤或夹层修复患者。发生脊髓梗塞的患者有235例(0.26%;95%可信区间(CI)为0.22%-0.29%)。在动脉瘤或夹层破裂的患者中,脊髓梗塞发生率为0.74%(95%CI为0.60%-0.88%),相比于没有破裂的动脉瘤患者的0.16%(95%CI为0.13%-0.19%)。在次要分析中,主动脉瘤或夹层破裂患者腔内修复后脊髓梗塞的发生率是相似的(0.91%;95%CI为0.62%-1.19%),与外科手术相比(0.68%;95%CI为0.53%-0.83%;P=0.147);然而,在未破裂的动脉瘤患者中脊髓梗塞的发生率在手术修复后(0.20%;95%CI为0.15%-0.25%)要高于腔内修复(0.11%;95%CI为0.08%-0.14%;P<0.001)。

由此可见,在主动脉夹层或主动脉瘤破裂患者修补术后脊髓梗死的发生约为每130例患者有1例,而在未破裂的主动脉瘤修复术后约为每600例患者出现1例。

原始出处:

Gino Gialdini,et al. Rates of Spinal Cord Infarction After Repair of Aortic Aneurysm or Dissection.Stroke. 2017. https://doi.org/10.1161/STROKEAHA.117.017071

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    2017-06-30 虈亣靌

    小编最牛!啥都知道

    0

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