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#兒童低級(jí)別膠質(zhì)瘤# 兒童低級(jí)別膠質(zhì)瘤（pLGG）是兒童中最常見(jiàn)的中樞神經(jīng)系統(tǒng)腫瘤，約占所有兒童腦腫瘤的30%。目前的治療包括手術(shù)切除、化療和MEK抑制劑，但對(duì)于復(fù)發(fā)或難以手術(shù)切除的病例，治療選擇有限。Tovorafenib是由Day One Biopharmaceuticals公司開(kāi)發(fā)的新型RAF抑制劑，主要用于治療BRAF基因改變的復(fù)發(fā)/難治性兒童低級(jí)別膠質(zhì)瘤（pLGG）。
