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在臨床上確實(shí)值得一試！事實(shí)上，除環(huán)孢霉素A外，其它的免疫抑制劑同樣也是一種選擇，如<a href='/topic/show?id=fbd825321ba' target=_blank style='color:#2F92EE;'>#他克莫司#</a>，<a href='/topic/show?id=73a8988297a' target=_blank style='color:#2F92EE;'>#雷帕霉素#</a>、<a href='/topic/show?id=614c105968e5' target=_blank style='color:#2F92EE;'>#霉酚酸脂#</a>，都值得進(jìn)行相關(guān)研究。, objectTitle=保胎成功率85%以上，環(huán)孢霉素A為什么有那么神奇嗎？, objectType=article, longId=768715, objectId=68e6e687155d, topicUrl=null, isHasObj=0, objectCover=https://img.medsci.cn/images/20230411/1f4972f00ef64ce4ad494f11bd8cf007.jpg, objectUrl=/article/show_article.do?id=68e6e687155d, replyNumber=1, likeNumber=170, createdTime=2023-04-25, rootId=0, userName=俠膽醫(yī)心, userId=f63e4754896, projectId=1, avatar=, status=1, hasArticle=1, attachment=null, ipAttribution=浙江省, moduleDTOList=[ModuleDTO(moduleId=68e6e687155d, moduleTitle=保胎成功率85%以上，環(huán)孢霉素A為什么有那么神奇嗎？, moduleType=article, hrefUrl=http://ermita.cn/article/show_article.do?id=68e6e687155d)], followStatus=false, userIsMember=false, type=1, lengthMark=0), GetTopicListResponse(id=811472, encodeId=27908114e264, content=<a href='/topic/show?id=60ff684932f' target=_blank style='color:#2F92EE;'>#環(huán)孢霉素A#</a>作為mTOR的抑制劑，對(duì)<a href='/topic/show?id=d11948e530e' target=_blank style='color:#2F92EE;'>#干細(xì)胞#</a>具有很強(qiáng)的調(diào)控作用，也被認(rèn)為具有抗衰老作用。因此，對(duì)<a href='/topic/show?id=53b810380450' target=_blank style='color:#2F92EE;'>#人牙周膜干細(xì)胞#</a>有調(diào)控作用，并不意外。同時(shí)，mTOR與AMPK信號(hào)通路也相互作用，這條信號(hào)通路在干細(xì)胞和<a href='/topic/show?id=4c239032154' target=_blank style='color:#2F92EE;'>#衰老#</a>中，都有不可估量的價(jià)值。目前藥物中，<a href='/topic/show?id=ce9d239823b' target=_blank style='color:#2F92EE;'>#二甲雙胍#</a>具有明確調(diào)控<a href='/topic/show?id=5ef410380524' target=_blank style='color:#2F92EE;'>#AMPK信號(hào)#</a>的作用，同時(shí)也具有抗衰老作用。因此，二甲雙胍若結(jié)合<a href='/topic/show?id=73a8988297a' target=_blank style='color:#2F92EE;'>#雷帕霉素#</a>類藥物，會(huì)不會(huì)真的可以駐顏不老？, objectTitle=J Periodontol：環(huán)孢菌素A對(duì)人牙周膜干細(xì)胞的作用, objectType=article, longId=196581, objectId=86b819658135, topicUrl=null, isHasObj=0, objectCover=https://img.medsci.cn/2020626/1593186478695_2456861.png, objectUrl=/article/show_article.do?id=86b819658135, replyNumber=0, likeNumber=345, createdTime=2020-08-20, rootId=0, userName=lovetcm, userId=7a3710, projectId=1, avatar=, status=1, hasArticle=1, attachment=null, ipAttribution=, moduleDTOList=[ModuleDTO(moduleId=86b819658135, moduleTitle=J Periodontol：環(huán)孢菌素A對(duì)人牙周膜干細(xì)胞的作用, moduleType=article, hrefUrl=http://ermita.cn/article/show_article.do?id=86b819658135)], followStatus=false, userIsMember=false, type=1, lengthMark=1)]
梅斯話題小助手
2020-05-29
