GetTopicDetailResponse(id=a2a41222241e, topicName=多替諾雷, introduction=, content=痛風(fēng) 高尿酸血癥 多替諾雷, image=null, comments=1, allHits=787, url=null, type=0, isShow=1, status=1, isAdmin=null, adminId=5395722, adminEncryptionId=cade5395722, adminName=梅斯管理員, createdBy=cade5395722, createdName=梅斯管理員, createdAvatar=, createdTime=Thu Dec 12 09:45:57 CST 2024, time=2024-12-12, bannerImg=https://img.medsci.cn/202167/1623032167418_5160405.png, bannerImgH5=https://img.medsci.cn/202167/1623032167418_5160405.png, likes=0, followStatus=false, moduleDTOList=null, tagId=499306, tagList=[TagDto(tagId=499306, tagName=多替諾雷)], ipAttribution=威斯康星, topicAdmin=0, lengthMark=0)
[GetTopicListResponse(id=2272719, encodeId=5ed722e27193b, content=<a href='/topic/show?id=69bbe11620e' target=_blank style='color:#2F92EE;'>#痛風(fēng)#</a> <a href='/topic/show?id=852f9939eda' target=_blank style='color:#2F92EE;'>#非布司他#</a> <a href='/topic/show?id=a2a41222241e' target=_blank style='color:#2F92EE;'>#多替諾雷#</a>, objectTitle=Arthritis Rheumatol：我國學(xué)者揭示多替諾雷與非布司他治療痛風(fēng)的療效和安全性, objectType=article, longId=886086, objectId=3b27886086bd, topicUrl=null, isHasObj=0, objectCover=https://img.medsci.cn/Random/hospital-staff-doctor-review-PTX6YZP.jpg, objectUrl=/article/show_article.do?id=3b27886086bd, replyNumber=0, likeNumber=24, createdTime=2025-07-09, rootId=0, userName=梅斯管理員, userId=cade5395722, projectId=1, avatar=, status=1, hasArticle=1, attachment=null, ipAttribution=上海, moduleDTOList=[ModuleDTO(moduleId=3b27886086bd, moduleTitle=Arthritis Rheumatol：我國學(xué)者揭示多替諾雷與非布司他治療痛風(fēng)的療效和安全性, moduleType=article, hrefUrl=http://ermita.cn/article/show_article.do?id=3b27886086bd)], followStatus=false, userIsMember=false, type=null, lengthMark=0), GetTopicListResponse(id=2267162, encodeId=c35f226e16257, content=<a href='/topic/show?id=69bbe11620e' target=_blank style='color:#2F92EE;'>#痛風(fēng)#</a> <a href='/topic/show?id=a2a41222241e' target=_blank style='color:#2F92EE;'>#多替諾雷#</a>, objectTitle=尿酸總降不下來？北大一院張卓莉團(tuán)隊(duì)：新藥讓74%中國患者尿酸達(dá)標(biāo)，比例近乎翻番！, objectType=article, longId=879551, objectId=052d8e9551c7, topicUrl=null, isHasObj=0, objectCover=https://img.medsci.cn/20240707/1720361307287_5579292.png, objectUrl=/article/show_article.do?id=052d8e9551c7, replyNumber=0, likeNumber=25, createdTime=2025-05-29, rootId=0, userName=梅斯管理員, userId=cade5395722, projectId=1, avatar=, status=1, hasArticle=1, attachment=null, ipAttribution=上海, moduleDTOList=[ModuleDTO(moduleId=052d8e9551c7, moduleTitle=尿酸總降不下來？北大一院張卓莉團(tuán)隊(duì)：新藥讓74%中國患者尿酸達(dá)標(biāo)，比例近乎翻番！, moduleType=article, hrefUrl=http://ermita.cn/article/show_article.do?id=052d8e9551c7)], followStatus=false, userIsMember=false, type=null, lengthMark=0), GetTopicListResponse(id=2241968, encodeId=1826224196899, content=<a href='/topic/show?id=69bbe11620e' target=_blank style='color:#2F92EE;'>#痛風(fēng)#</a> <a href='/topic/show?id=4b1a1023444e' target=_blank style='color:#2F92EE;'>#高尿酸血癥#</a> <a href='/topic/show?id=a2a41222241e' target=_blank style='color:#2F92EE;'>#多替諾雷#</a>, objectTitle=CDE批準(zhǔn)多替諾雷上市，用于痛風(fēng)伴高尿酸血癥, objectType=article, longId=854977, objectId=3bcf8549e7eb, topicUrl=null, isHasObj=0, objectCover=https://img.medsci.cn/images/20241101/5ae7539d31914752b79b3578c11d5c14-sLfK6egHTest.jpg, objectUrl=/article/show_article.do?id=3bcf8549e7eb, replyNumber=0, likeNumber=0, createdTime=2024-12-12, rootId=0, userName=梅斯管理員, userId=cade5395722, projectId=1, avatar=, status=1, hasArticle=1, attachment=null, ipAttribution=威斯康星, moduleDTOList=[ModuleDTO(moduleId=3bcf8549e7eb, moduleTitle=CDE批準(zhǔn)多替諾雷上市，用于痛風(fēng)伴高尿酸血癥, moduleType=article, hrefUrl=http://ermita.cn/article/show_article.do?id=3bcf8549e7eb)], followStatus=false, userIsMember=false, type=null, lengthMark=0), GetTopicListResponse(id=2241972, encodeId=f41122419e203, content=CDE批準(zhǔn)<a href='/topic/show?id=a2a41222241e' target=_blank style='color:#2F92EE;'>#多替諾雷#</a>上市，用于<a href='/topic/show?id=69bbe11620e' target=_blank style='color:#2F92EE;'>#痛風(fēng)#</a>伴<a href='/topic/show?id=4b1a1023444e' target=_blank style='color:#2F92EE;'>#高尿酸血癥#</a>，<a href='/topic/show?id=60c232154fc' target=_blank style='color:#2F92EE;'>#創(chuàng)新藥物#</a>
整體而言，多替諾雷與<a href='/topic/show?id=f1a68e07003' target=_blank style='color:#2F92EE;'>#苯溴馬隆#</a>療效是近似的，但是安全性好太多。苯溴馬隆本來也是好藥，只是毒性太大，臨床上應(yīng)用受限，現(xiàn)在多替諾雷是很好的替代品。
另外，從原理性講，它還能與<a href='/topic/show?id=852f9939eda' target=_blank style='color:#2F92EE;'>#非布司他#</a>等其它藥物，具有協(xié)同效應(yīng)，因?yàn)樗鼈冏饔脵C(jī)制不同。
, objectTitle=CDE批準(zhǔn)多替諾雷上市，用于痛風(fēng)伴高尿酸血癥, objectType=article, longId=854977, objectId=3bcf8549e7eb, topicUrl=null, isHasObj=0, objectCover=https://img.medsci.cn/images/20241101/5ae7539d31914752b79b3578c11d5c14-sLfK6egHTest.jpg, objectUrl=/article/show_article.do?id=3bcf8549e7eb, replyNumber=0, likeNumber=75, createdTime=2024-12-12, rootId=0, userName=俠膽醫(yī)心, userId=f63e4754896, projectId=1, avatar=, status=1, hasArticle=1, attachment=[AttachmentDto(url=https://img.medsci.cn/comment/27e7c24bf93a40ee87ff87a21cf624e8-gdTzMI6Vx79n.webp, type=image, width=0, height=0)], ipAttribution=威斯康星, moduleDTOList=[ModuleDTO(moduleId=3bcf8549e7eb, moduleTitle=CDE批準(zhǔn)多替諾雷上市，用于痛風(fēng)伴高尿酸血癥, moduleType=article, hrefUrl=http://ermita.cn/article/show_article.do?id=3bcf8549e7eb)], followStatus=false, userIsMember=false, type=1, lengthMark=1)]
梅斯管理員
2024-12-12發(fā)表于威斯康星
