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[GetTopicListResponse(id=2244691, encodeId=f8a22244691e9, content=<a href='/topic/show?id=ca06102195ec' target=_blank style='color:#2F92EE;'>#高凝狀態(tài)#</a> <a href='/topic/show?id=799a122e38a6' target=_blank style='color:#2F92EE;'>#急性重度潰瘍性結(jié)腸炎#</a>, objectTitle=CGH：急性重度潰瘍性結(jié)腸炎患者出院后的高凝狀態(tài), objectType=article, longId=856672, objectId=9b218566e270, topicUrl=null, isHasObj=0, objectCover=https://img.medsci.cn/20241219/1734601422307_8538692.png, objectUrl=/article/show_article.do?id=9b218566e270, replyNumber=0, likeNumber=49, createdTime=2024-12-24, rootId=0, userName=梅斯管理員, userId=cade5395722, projectId=1, avatar=, status=1, hasArticle=1, attachment=null, ipAttribution=陜西省, moduleDTOList=[ModuleDTO(moduleId=9b218566e270, moduleTitle=CGH：急性重度潰瘍性結(jié)腸炎患者出院后的高凝狀態(tài), moduleType=article, hrefUrl=http://ermita.cn/article/show_article.do?id=9b218566e270)], followStatus=false, userIsMember=false, type=null, lengthMark=0), GetTopicListResponse(id=2162681, encodeId=5c662162681b0, content=<a href='/topic/show?id=f0838291817' target=_blank style='color:#2F92EE;'>#腫瘤微環(huán)境#</a>包括<a href='/topic/show?id=a67610695ea7' target=_blank style='color:#2F92EE;'>#基質(zhì)微環(huán)境#</a><a href='/topic/show?id=029e2901e8e' target=_blank style='color:#2F92EE;'>#免疫微環(huán)境#</a>等多種微環(huán)境因素交織，里面包括<a href='/topic/show?id=dd51830363f' target=_blank style='color:#2F92EE;'>#腫瘤相關(guān)成纖維細(xì)胞#</a>，<a href='/topic/show?id=f7d683034e8' target=_blank style='color:#2F92EE;'>#腫瘤相關(guān)巨噬細(xì)胞#</a>，<a href='/topic/show?id=76bf8290642' target=_blank style='color:#2F92EE;'>#腫瘤干細(xì)胞#</a>，<a href='/topic/show?id=4ce783062c7' target=_blank style='color:#2F92EE;'><a href='/topic/show?id=4ce783062c7' target=_blank style='color:#2F92EE;'>#腫瘤細(xì)胞#</a></a>，<a href='/topic/show?id=ae97180090b' target=_blank style='color:#2F92EE;'>#T細(xì)胞#</a>，<a href='/topic/show?id=310d383ef5' target=_blank style='color:#2F92EE;'>#B細(xì)胞#</a>，<a href='/topic/show?id=6ea85e6117' target=_blank style='color:#2F92EE;'>#DC細(xì)胞#</a>，<a href='/topic/show?id=ca06102195ec' target=_blank style='color:#2F92EE;'>#高凝狀態(tài)#</a>，以及正在處于壞死或<a href='/topic/show?id=6f65e52572c' target=_blank style='color:#2F92EE;'>#程序性壞死#</a>的腫瘤細(xì)胞，共同構(gòu)成的復(fù)雜微環(huán)境，這些微環(huán)境有助于保護(hù)腫瘤細(xì)胞免受藥物的攻擊。同時(shí)，腫瘤細(xì)胞自身也不斷改變自己的狀態(tài)，包括腫瘤細(xì)胞膜的硬度，腫瘤細(xì)胞表面的蛋白，腫瘤細(xì)胞<a href='/topic/show?id=ba2b2549371' target=_blank style='color:#2F92EE;'>#代謝重編程#</a>等，從而減少被<a href='/topic/show?id=afc929130ad' target=_blank style='color:#2F92EE;'>#免疫細(xì)胞#</a>的識(shí)別，同時(shí)更有利于與<a href='/topic/show?id=430750648d8' target=_blank style='color:#2F92EE;'>#微環(huán)境#</a>配合，以及有助于<a href='/topic/show?id=137a831151a' target=_blank style='color:#2F92EE;'>#腫瘤轉(zhuǎn)移#</a>。
未來(lái)需要針對(duì)這些因素共同的作用，將<a href='/topic/show?id=4ce783062c7' target=_blank style='color:#2F92EE;'><a href='/topic/show?id=4ce783062c7' target=_blank style='color:#2F92EE;'>#腫瘤細(xì)胞#</a></a>轉(zhuǎn)化為正常細(xì)胞，即讓壞人改造為正常人，可以設(shè)置監(jiān)獄，即通過(guò)某種措施將腫瘤細(xì)胞禁錮在局部，不允許其轉(zhuǎn)移，梅斯小編暫且稱(chēng)之為“<a href='/topic/show?id=b7b410695867' target=_blank style='color:#2F92EE;'>#腫瘤細(xì)胞監(jiān)獄#</a>”，并通過(guò)藥物治療，將其轉(zhuǎn)化為正常細(xì)胞，這可能是一種新的途徑，而不只是一味地抑制或殺死!
有興趣的同仁可以在此跟貼進(jìn)行討論。, objectTitle=重磅綜述：腫瘤微環(huán)境, objectType=article, longId=786975, objectId=6261e8697554, topicUrl=null, isHasObj=0, objectCover=https://img.medsci.cn/Random/doctor-writing.jpg, objectUrl=/article/show_article.do?id=6261e8697554, replyNumber=0, likeNumber=295, createdTime=2023-10-14, rootId=0, userName=俠膽醫(yī)心, userId=f63e4754896, projectId=1, avatar=, status=1, hasArticle=1, attachment=null, ipAttribution=加利福尼亞, moduleDTOList=[ModuleDTO(moduleId=6261e8697554, moduleTitle=重磅綜述：腫瘤微環(huán)境, moduleType=article, hrefUrl=http://ermita.cn/article/show_article.do?id=6261e8697554)], followStatus=false, userIsMember=false, type=1, lengthMark=1), GetTopicListResponse(id=904243, encodeId=4b7a90424351, content=<a href='/topic/show?id=d8dbe130197' target=_blank style='color:#2F92EE;'>#癌癥#</a>患者的<a href='/topic/show?id=5471991e9f3' target=_blank style='color:#2F92EE;'>#靜脈血栓栓塞#</a><a href='/topic/show?id=4a481855350' target=_blank style='color:#2F92EE;'>#VTE#</a>風(fēng)險(xiǎn)，這可能有多種原因，其一現(xiàn)在的治療多是免疫治療和靶向治療，其二，患者的生存期延長(zhǎng)，<a href='/topic/show?id=aa0582e6946' target=_blank style='color:#2F92EE;'>#腫瘤#</a>患者多是<a href='/topic/show?id=ca06102195ec' target=_blank style='color:#2F92EE;'>#高凝狀態(tài)#</a>，容易并發(fā)血栓。同時(shí)，如果適當(dāng)?shù)?lt;a href='/topic/show?id=606b55e4466' target=_blank style='color:#2F92EE;'>#抗血小板#</a>和<a href='/topic/show?id=353b55219b8' target=_blank style='color:#2F92EE;'>#抗凝#</a>治療，可能會(huì)有利于改善<a href='/topic/show?id=f0838291817' target=_blank style='color:#2F92EE;'>#腫瘤微環(huán)境#</a>，有利于治療。, objectTitle=Blood：1997年-2017年癌癥患者的靜脈血栓栓塞風(fēng)險(xiǎn)變化, objectType=article, longId=203916, objectId=4d2220391612, topicUrl=null, isHasObj=0, objectCover=https://img.medsci.cn/Random/type2diabetes-s18-plaque-in-artery.jpg, objectUrl=/article/show_article.do?id=4d2220391612, replyNumber=0, likeNumber=474, createdTime=2020-12-02, rootId=0, userName=lifefamily@163, userId=a33789389, projectId=1, avatar=, status=1, hasArticle=1, attachment=null, ipAttribution=, moduleDTOList=[ModuleDTO(moduleId=4d2220391612, moduleTitle=Blood：1997年-2017年癌癥患者的靜脈血栓栓塞風(fēng)險(xiǎn)變化, moduleType=article, hrefUrl=http://ermita.cn/article/show_article.do?id=4d2220391612)], followStatus=false, userIsMember=false, type=1, lengthMark=0)]
梅斯話題小助手
2020-05-29
