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#前列環(huán)素# 我們對Tello等人最近的研究表示濃厚的興趣,他們聲稱吸入型依洛前列素能在導管室和實驗性束帶模型中迅速增加右心室(RV)收縮能力。然而,我們認為前列環(huán)素相關的RV收縮能力和RV-肺動脈(PA)耦合可能取決于所評估的疾病階段。作者在具有中度后負荷(約0.66 mm Hg/ml)的肺動脈高壓(PAH)患者中展示了吸入型依洛前列素對RV收縮能力的急性5分鐘效應。