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Since beginning publication in 1950, CA: A Cancer Journal for Clinicians has served as the flagship journal for the American Cancer Society, providing a peer-reviewed publication containing solicited review articles of interest to oncologists, primary care physicians, nurses, and other health care professionals interested in best practices for cancer prevention, early detection, and treatment. Although CA is an oncology journal, it is not a journal only for oncologists. Published six times per year, CA is the most widely circulated oncology journal in the world, mailing to over 100,000 individuals.