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#血清尿酸水平# 慢性腎臟?。–KD）患者中高尿酸血癥和痛風(fēng)的患病率顯著升高，是心血管事件和腎功能惡化的重要危險(xiǎn)因素。鈉-葡萄糖協(xié)同轉(zhuǎn)運(yùn)蛋白2（SGLT2）抑制劑通過(guò)促進(jìn)尿糖排泄改善腎臟結(jié)局，但其對(duì)尿酸代謝的影響尚不明確。EMPA-KIDNEY試驗(yàn)旨在評(píng)估恩格列凈（empagliflozin）對(duì)CKD患者血清尿酸水平及痛風(fēng)風(fēng)險(xiǎn)的療效，探索其在不同基線特征（如估算腎小球?yàn)V過(guò)率[eGFR]、糖尿病狀態(tài)）患者中的差異化作用，為臨床決策提供依據(jù)。
