GetTopicDetailResponse(id=86f8192107e, topicName=β1受體阻滯劑, introduction=β1受體阻滯劑, content=null, image=null, comments=1, allHits=1845, url=https://h5.medsci.cn/topic?id=19210, type=0, isShow=1, status=1, isAdmin=null, adminId=1, adminEncryptionId=1eae1, adminName=小M, createdBy=null, createdName=, createdAvatar=, createdTime=Fri May 29 21:19:53 CST 2020, time=2020-05-29, bannerImg=https://img.medsci.cn/202167/1623032167418_5160405.png, bannerImgH5=https://img.medsci.cn/202167/1623032167418_5160405.png, likes=0, followStatus=false, moduleDTOList=null, tagId=77810, tagList=[TagDto(tagId=77810, tagName=β1受體阻滯劑)], ipAttribution=, topicAdmin=1, lengthMark=0)
[GetTopicListResponse(id=2164520, encodeId=638a21645200f, content=仔細(xì)閱讀了本文,十分精彩!!!不管是研究,還是討論!
<a href='/topic/show?id=2a622434820' target=_blank style='color:#2F92EE;'>#交感神經(jīng)#</a>興奮---><a href='/topic/show?id=c72b2854039' target=_blank style='color:#2F92EE;'>#兒茶酚胺#</a>釋放-->β1-腎上腺素受體<a href='/topic/show?id=6f9310e20228' target=_blank style='color:#2F92EE;'>#ADRB1#</a>激活--><a href='/topic/show?id=21a71803689' target=_blank style='color:#2F92EE;'>#T細(xì)胞耗竭#</a>--><a href='/topic/show?id=a07f82814ec' target=_blank style='color:#2F92EE;'>#腫瘤免疫治療#</a>效果下降。這個(gè)邏輯是成立的,但是同樣需要考慮交感神經(jīng)在腫瘤中的雙面作用。交感神經(jīng)興奮,可以調(diào)動(dòng)人體更多的資源對(duì)抗<a href='/topic/show?id=aa0582e6946' target=_blank style='color:#2F92EE;'>#腫瘤#</a>,但是過(guò)度興奮,又可能抑制免疫功能,從而讓腫瘤生長(zhǎng)更快。
未來(lái)<a href='/topic/show?id=86f8192107e' target=_blank style='color:#2F92EE;'>#β1受體阻滯劑#</a>可以在<a href='/topic/show?id=330410333110' target=_blank style='color:#2F92EE;'>#黑色素瘤#</a>,<a href='/topic/show?id=384b8220449' target=_blank style='color:#2F92EE;'>#肺癌#</a>,<a href='/topic/show?id=843a85e9421' target=_blank style='color:#2F92EE;'>#膀胱癌#</a>等<a href='/topic/show?id=ca3610e203ba' target=_blank style='color:#2F92EE;'>#免疫敏感性腫瘤#</a>中,與<a href='/topic/show?id=0de5290588c' target=_blank style='color:#2F92EE;'>#免疫檢查點(diǎn)抑制劑#</a>聯(lián)合應(yīng)用,值得做一些<a href='/topic/show?id=44cee263861' target=_blank style='color:#2F92EE;'>#真實(shí)世界研究#</a>,或發(fā)起臨床試驗(yàn)的。
當(dāng)然,<a href='/topic/show?id=148562431a3' target=_blank style='color:#2F92EE;'>#梅斯醫(yī)學(xué)#</a>小編提到<a href='/topic/show?id=0d3240e64e' target=_blank style='color:#2F92EE;'>#CAR-T細(xì)胞治療#</a>中的嘗試應(yīng)用,這個(gè)十分有興趣的話題。, objectTitle=Nature:交感神經(jīng)興奮可能是腫瘤患者免疫T細(xì)胞耗竭的關(guān)鍵因素, objectType=article, longId=797576, objectId=a4f8e975761a, topicUrl=null, isHasObj=0, objectCover=https://img.medsci.cn/images/20231023/c2b04529fb2245019c7d0a808ff808e3.jpg, objectUrl=/article/show_article.do?id=a4f8e975761a, replyNumber=0, likeNumber=207, createdTime=2023-10-24, rootId=0, userName=俠膽醫(yī)心, userId=f63e4754896, projectId=1, avatar=, status=1, hasArticle=1, attachment=null, ipAttribution=上海, moduleDTOList=[ModuleDTO(moduleId=a4f8e975761a, moduleTitle=Nature:交感神經(jīng)興奮可能是腫瘤患者免疫T細(xì)胞耗竭的關(guān)鍵因素, moduleType=article, hrefUrl=http://ermita.cn/article/show_article.do?id=a4f8e975761a)], followStatus=false, userIsMember=false, type=1, lengthMark=1)]
梅斯話題小助手
2020-05-29