GetTopicDetailResponse(id=a20712e4331c, topicName=177Lu-FAPI-04, introduction=, content=心肌梗死 177Lu-FAPI-04, image=null, comments=1, allHits=253, url=null, type=0, isShow=1, status=1, isAdmin=null, adminId=5395722, adminEncryptionId=cade5395722, adminName=梅斯管理員, createdBy=cade5395722, createdName=梅斯管理員, createdAvatar=, createdTime=Fri May 30 19:19:45 CST 2025, time=2025-05-30, bannerImg=https://img.medsci.cn/202167/1623032167418_5160405.png, bannerImgH5=https://img.medsci.cn/202167/1623032167418_5160405.png, likes=0, followStatus=false, moduleDTOList=null, tagId=505105, tagList=[TagDto(tagId=505105, tagName=177Lu-FAPI-04)], ipAttribution=上海, topicAdmin=0, lengthMark=0)
[GetTopicListResponse(id=2267370, encodeId=1c07226e3709e, content=<a href='/topic/show?id=b086512e33c' target=_blank style='color:#2F92EE;'>#心肌梗死#</a> <a href='/topic/show?id=a20712e4331c' target=_blank style='color:#2F92EE;'>#177Lu-FAPI-04#</a>, objectTitle=MedComm 南醫(yī)大二附院周祥教授團(tuán)隊(duì)首次發(fā)現(xiàn)177Lu-FAPI-04可用于心肌梗死的靶向治療, objectType=article, longId=879801, objectId=30408e98014d, topicUrl=null, isHasObj=0, objectCover=https://img.medsci.cn/20230326/1679867384393_4754896.png, objectUrl=/article/show_article.do?id=30408e98014d, replyNumber=0, likeNumber=45, createdTime=2025-05-30, rootId=0, userName=梅斯管理員, userId=cade5395722, projectId=1, avatar=, status=1, hasArticle=1, attachment=null, ipAttribution=上海, moduleDTOList=[ModuleDTO(moduleId=30408e98014d, moduleTitle=MedComm 南醫(yī)大二附院周祥教授團(tuán)隊(duì)首次發(fā)現(xiàn)177Lu-FAPI-04可用于心肌梗死的靶向治療, moduleType=article, hrefUrl=http://ermita.cn/article/show_article.do?id=30408e98014d)], followStatus=false, userIsMember=false, type=null, lengthMark=0), GetTopicListResponse(id=2267390, encodeId=4224226e390ba, content=<a href='/topic/show?id=a20712e4331c' target=_blank style='color:#2F92EE;'>#177Lu-FAPI-04#</a> 心肌梗死是全球致死率最高的心血管疾病，患者即使經(jīng)介入手術(shù)恢復(fù)血流，仍面臨心肌纖維化導(dǎo)致的不可逆性心功能損傷。雖然心肌纖維化能在一定程度上修復(fù)受損的心臟組織，防止心室破裂，然而過(guò)度纖維化是有害的，它會(huì)引起心室壁僵硬，心臟順應(yīng)性降低，最終可導(dǎo)致心力衰竭。因此，尋找心肌纖維化的有效治療靶點(diǎn)，對(duì)于改善心肌梗死的預(yù)后具有重要意義。, objectTitle=177Lu-FAPI-04, objectType=topic, longId=127433, objectId=null, topicUrl=null, isHasObj=0, objectCover=null, objectUrl=null, replyNumber=0, likeNumber=18, createdTime=2025-05-30, rootId=0, userName=yangchou, userId=88b489038, projectId=1, avatar=, status=1, hasArticle=0, attachment=null, ipAttribution=浙江省, moduleDTOList=null, followStatus=false, userIsMember=false, type=1, lengthMark=1)]
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#177Lu-FAPI-04# 心肌梗死是全球致死率最高的心血管疾病，患者即使經(jīng)介入手術(shù)恢復(fù)血流，仍面臨心肌纖維化導(dǎo)致的不可逆性心功能損傷。雖然心肌纖維化能在一定程度上修復(fù)受損的心臟組織，防止心室破裂，然而過(guò)度纖維化是有害的，它會(huì)引起心室壁僵硬，心臟順應(yīng)性降低，最終可導(dǎo)致心力衰竭。因此，尋找心肌纖維化的有效治療靶點(diǎn)，對(duì)于改善心肌梗死的預(yù)后具有重要意義。
