GetTopicDetailResponse(id=f51fe4158e6, topicName=神經(jīng)保護(hù)劑, introduction=神經(jīng)保護(hù)劑, content=null, image=null, comments=2, allHits=1773, url=https://h5.medsci.cn/topic?id=74158, type=0, isShow=1, status=1, isAdmin=null, adminId=1, adminEncryptionId=1eae1, adminName=小M, createdBy=null, createdName=, createdAvatar=, createdTime=Fri May 29 21:19:53 CST 2020, time=2020-05-29, bannerImg=https://img.medsci.cn/202167/1623032167418_5160405.png, bannerImgH5=https://img.medsci.cn/202167/1623032167418_5160405.png, likes=0, followStatus=false, moduleDTOList=null, tagId=8767, tagList=[TagDto(tagId=8767, tagName=神經(jīng)保護(hù)劑)], ipAttribution=, topicAdmin=1, lengthMark=0)
[GetTopicListResponse(id=2206758, encodeId=40702206e5895, content=<a href='/topic/show?id=88235533945' target=_blank style='color:#2F92EE;'>#抗抑郁藥#</a> <a href='/topic/show?id=f51fe4158e6' target=_blank style='color:#2F92EE;'>#神經(jīng)保護(hù)劑#</a>, objectTitle=SVN:具有快速起效抗抑郁和抗焦慮作用的新型抗中風(fēng)藥物 ZL006-05 的臨床前評估, objectType=article, longId=826622, objectId=f881826622bd, topicUrl=null, isHasObj=0, objectCover=https://img.medsci.cn/20240523/1716475003910_5579292.jpg, objectUrl=/article/show_article.do?id=f881826622bd, replyNumber=0, likeNumber=120, createdTime=2024-05-26, rootId=0, userName=梅斯管理員, userId=cade5395722, projectId=1, avatar=, status=1, hasArticle=1, attachment=null, ipAttribution=上海, moduleDTOList=[ModuleDTO(moduleId=f881826622bd, moduleTitle=SVN:具有快速起效抗抑郁和抗焦慮作用的新型抗中風(fēng)藥物 ZL006-05 的臨床前評估, moduleType=article, hrefUrl=http://ermita.cn/article/show_article.do?id=f881826622bd)], followStatus=false, userIsMember=false, type=null, lengthMark=0), GetTopicListResponse(id=2117834, encodeId=50f9211e8341a, content=激活<a href='/topic/show?id=afa5965438d' target=_blank style='color:#2F92EE;'>#鐵死亡#</a>,增強(qiáng)<a href='/topic/show?id=370d8126914' target=_blank style='color:#2F92EE;'>#肝癌#</a><a href='/topic/show?id=daf52906537' target=_blank style='color:#2F92EE;'>#免疫治療#</a>效果。這里使用的是鐵死亡激活劑<a href='/topic/show?id=299e10542295' target=_blank style='color:#2F92EE;'>#Withaferin A#</a>。Withaferin A ,可以譯為魏菲靈A或<a href='/topic/show?id=aab595622d5' target=_blank style='color:#2F92EE;'>#醉茄素A#</a>,是從<a href='/topic/show?id=eb2e1054234a' target=_blank style='color:#2F92EE;'>#睡茄#</a>中分離到的甾體內(nèi)酯,可以對硫代*基化敏感的<a href='/topic/show?id=6b416398956' target=_blank style='color:#2F92EE;'>#氧化還原#</a>機(jī)制阻止<a href='/topic/show?id=3879828e19d' target=_blank style='color:#2F92EE;'>#腫瘤壞死因子#</a>誘導(dǎo)的IκB激酶β的激活,從而抑制<a href='/topic/show?id=f1c512e304f' target=_blank style='color:#2F92EE;'>#NF-kB#</a>的活性,靶作用于<a href='/topic/show?id=9d521054247a' target=_blank style='color:#2F92EE;'>#波形蛋白#</a> (vimentin),具有抗炎,<a href='/topic/show?id=2392556299f' target=_blank style='color:#2F92EE;'>#抗腫瘤#</a>等功效。Withaferin A 是<a href='/topic/show?id=5de210542595' target=_blank style='color:#2F92EE;'>#內(nèi)皮蛋白C受體#</a>(EPCR)脫落的抑制劑。
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梅斯話題小助手
2020-05-29