The American Journal of Physiology - Lung Cellular and Molecular Physiology publishes original research covering the broad scope of molecular, cellular, and integrative aspects of normal and abnormal function of cells and components of the respiratory system. Areas of interest include the nose and sinuses, conducting airways, pulmonary circulation, lung endothelial and epithelial cells, the pleura, neuroendocrine and immunologic cells in the lung, neural cells involved in control of breathing, and cells of the diaphragm and thoracic muscles. The processes to be covered in the Journal include gas exchange, metabolic control at the cellular level, intracellular signaling, gene expression, genomics, macromolecules and their turnover, cell-cell and cell-matrix interactions, cell motility, secretory mechanisms, membrane function, surfactant, matrix components, mucus and lining materials, lung defenses, macrophage function, transport of salt, water and protein, development and differentiation of the respiratory system, and response to the environment. Reports of research using innovative approaches in cell and organ physiology, molecular and cell biology, molecular genetics, genomics including animal models of integrative function, biochemistry, biophysics, and morphology are welcome. The Journal will also encourage novel submission of findings of the pathophysiology of the respiratory system at organ, cellular and molecular levels including studies in human subjects.